Start Low, Go Slow: A Cannabis Dosing Guide
Short answer: "Start low, go slow" means trying a small amount of a new product, then waiting long enough to feel its full effect before taking more. Timing is the key. With inhaled THC, effects start within seconds to a few minutes, peak after 15–30 minutes, and taper off within 2–3 hours. With oral THC (edibles), effects start 30–90 minutes after you eat it, peak at 2–3 hours, and can last about 4–12 hours (Grotenhermen 2003). That delay is why people sometimes take more edible before the first dose has kicked in. This guide explains the timing and how to read potency. It doesn't prescribe doses, which depend on the person and the product. Talk to a healthcare provider about your own situation.
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Why "start low, go slow"
The most important acute adverse effects of too much THC are anxiety and panic attacks, along with increased heart rate and changes in blood pressure (Grotenhermen 2003). NIDA says anxiety, fear and panic are more common with large amounts, high-THC products, or little experience (NIDA). Starting with a small amount and waiting lowers the chance of taking more than you meant to.
Reading potency on a DC label
- Flower, vapes and concentrates list THC as a percentage by weight.
- Edibles, tinctures and capsules list THC in milligrams (mg), per package and usually per serving.
- Labels and COAs often show THCA. Total THC = THC + (0.877 × THCA). See how to read a COA.
Potency has gone up over time. In DEA-seized cannabis, average THC rose from about 4% in 1995 to about 12% in 2014 (ElSohly et al. 2016). NIDA notes that dispensary flower and concentrates can exceed 40% THC (NIDA). Two products with the same name can differ a lot, so read the label every time.
DC's specific per-serving and per-package THC limits for edibles aren't covered in our sources. They're UNKNOWN to this page; check 22-C DCMR or ask ABCA.
Timing by method
| Method | Effects start | Peak | Taper/duration | Source |
|---|---|---|---|---|
| Inhaled (smoked or vaporized) | Seconds to a few minutes | 15–30 min | Taper within 2–3 hours | Grotenhermen 2003 |
| Oral (edibles, capsules) | 30–90 min | 2–3 hours | About 4–12 hours, depending on dose and effect | Grotenhermen 2003 |
| Sublingual tincture | UNKNOWN | UNKNOWN | UNKNOWN | Grotenhermen notes sublingual use "only in a few studies" |
Oral THC is absorbed more slowly and less predictably than inhaled THC (Huestis 2007). For a full comparison, see consumption methods.
The practical version
- Read the label. Note the % or mg of THC, and CBD if listed.
- New product, small amount. Even experienced users should treat a new product as unknown.
- Wait out the window. With inhaled THC, wait until you've reached the peak (about 15–30 minutes) before deciding on more. With edibles, wait at least the full onset window (up to 90 minutes), keeping in mind the peak may not come until 2–3 hours (Grotenhermen 2003).
- Don't mix with alcohol or other substances, and don't drive. NIDA and NCCIH both describe impaired driving as a risk (NIDA; NCCIH).
- Ask about interactions. CBD can interact with other medicines (NCCIH).
Tolerance
Regular use can lead to dependency and a mild withdrawal syndrome (Grotenhermen 2003). NIDA estimates cannabis use disorder affects about 22–30% of people who use cannabis (NIDA). How long a break "resets" tolerance is UNKNOWN. We haven't found a reliable human source for specific timelines, so we don't publish them.
If someone has taken too much
- Move to a calm, safe place. Don't drive.
- Effects of oral THC can last many hours (Grotenhermen 2003).
- Get medical help for chest pain, trouble breathing, fainting, severe vomiting, confusion, or if a child or pet may have eaten cannabis. Call 911 in an emergency. Poison Control is 1-800-222-1222.
Frequently asked questions
What does "start low, go slow" mean?
Try a small amount of a new product and wait for its full effect before taking more. Oral THC can take 30–90 minutes to start and 2–3 hours to peak (Grotenhermen 2003).
How long do edibles take to kick in?
Effects typically start 30–90 minutes after eating, peak at 2–3 hours, and last about 4–12 hours (Grotenhermen 2003).
How long does smoking or vaping last?
Effects start within seconds to minutes, peak at 15–30 minutes, and taper within 2–3 hours (Grotenhermen 2003).
How much should I take?
We don't recommend specific doses. Read the label, start small with any new product, and talk to a healthcare provider, especially if you take other medicines.
Keep reading
More in this topic
Sources
- Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327–360. PMID 12648025: https://pubmed.ncbi.nlm.nih.gov/12648025/
- Huestis MA. Human cannabinoid pharmacokinetics. Chem Biodivers. 2007: https://pmc.ncbi.nlm.nih.gov/articles/PMC2689518/
- ElSohly MA, et al. Changes in Cannabis Potency Over the Last 2 Decades (1995–2014). Biol Psychiatry. 2016: https://pmc.ncbi.nlm.nih.gov/articles/PMC4987131/
- NIDA, "Cannabis (Marijuana)": https://nida.nih.gov/publications/research-reports/marijuana/what-marijuana
- NCCIH, "Cannabis (Marijuana) and Cannabinoids: What You Need To Know": https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
Last updated: October 26, 2026. Educational information only, not medical advice. 21+.